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Novel syntheses of densely functionalized indolizines, di- and tetrahydroindolizines from 2-formyl-1,4-dihydropyridine systems based on cascade process

Identifieur interne : 001005 ( France/Analysis ); précédent : 001004; suivant : 001006

Novel syntheses of densely functionalized indolizines, di- and tetrahydroindolizines from 2-formyl-1,4-dihydropyridine systems based on cascade process

Auteurs : Štefan Marchal N ; Katar Na Cvopová ; Duy-Phong Pham-Huu ; Miloslav Chud K ; Jozef Kozisek ; Ingrid Svoboda [Allemagne] ; Adam Da Ch [France]

Source :

RBID : ISTEX:FBCBC4836260819E203EA10D05D8FBE03FBD7B6B

English descriptors

Abstract

Several indolizines, di- and tetrahydroindolizines have been synthesized successfully in a one-pot procedure, in two or three steps from 2-formyl-1,4-dihydropyridine derivatives and malonitrile in 57–87% yield. The general mechanism leading to these azacyclic compounds, involving 2-dicyanovinyl-1,4-dihydropyridines, is discussed.

Url:
DOI: 10.1016/S0040-4039(01)01054-1


Affiliations:


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ISTEX:FBCBC4836260819E203EA10D05D8FBE03FBD7B6B

Le document en format XML

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   |texte=   Novel syntheses of densely functionalized indolizines, di- and tetrahydroindolizines from 2-formyl-1,4-dihydropyridine systems based on cascade process
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